| Applications: | Bioactivity, SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 16.3 kDa (142aa), confirmed by MALDI-TOF. |
| Purity: | > 90% by SDS PAGE |
| Description: | Vascular endothelial growth factor (VEGF) is homodimeric, heparin-binding glycoprotein involved in both angiogenesis and vasculogenesis. VEGF is expressed as multiple alternately spliced isoforms of VEGF121, 165, 189 and 206. VEGF binds to the receptor tyrosine kinases VEGF R1 (Flt-1) and VEGF R2 (KDR/Flk-1) to activate signal transduction and regulate both physiological and pathological angiogenesis. Recombinant VEGF121 protein was expressed in E. coli and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MAPMAEGGGQ NHHEVVKFMD VYQRSYCHPI ETLVDIFQEY PDEIEYIFKP SCVPLMRCGG CCNDEGLECV PTEESNITMQ IMRIKPHQGQ HIGEMSFLQH NKCECRPKKD RARQEKCDKP RR |
| Synonym: | Vascular endothelial growth factor A isoform f, VPF, VEGF, VEGF-A, MGC70609, VEGF121, Vascular endothelial growth factor A isoform f, Vascular endothelial growth factor A isoform f MVCD1, Vascular endothelial growth factor A, Vascular permeability factor, VEGF A. |
| Ascension Number: | P15692 |
| NCBI EntrezGene: | NP_001020541 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
