| Description: | Human ubquitin-conjugating enzyme 7 (ubcH7) is a ubiquitin-conjugating enzyme (E2) mediating c-fos degradation, transcription factor NF-kappa B maturation, and human papilloma virus-mediated p53 and Myc protein degradation, in vitro. The ubiquitin-conjugating enzymes (E2s) are essential components of the post-translational protein ubiquitination pathway, mediating the transfer of activated ubiquitin to substrate proteins. The human uBE2L1-uBE2L4 gene could potentially encode different isoforms of the ubcH7. uBE2L3 gene, located at chromosome 22q11. 2, is the only identical family member with introns and encodes a polypeptide sequence identical to that of ubcH7. ubcH7 (154amino acid) was over-expressed in E. coli and purified by using conventional chromatography techniques. |
| Synonym: | ubiquitin-conjugating enzyme E2L 3, uBE2G1, uBE2G, ubc7 (ubiquitin Conjugating enzyme 7), EC 6.3.2.19, ubiquitin-protein ligase G1, ubiquitin carrier protein G1, E217K, uBC7, ubiquitin-conjugating enzyme E2 G1, ubiquitin-conjugating enzyme E2L 3 uBC 7, uBC7 homolog yeast, uBE 2G, ubiquitin conjugating enzyme E2 G1, ubiquitin conjugating enzyme E2G 1 (homologous to C, elegans uBC7), ubiquitin conjugating enzyme E2G 1 (uBC7 homolog C, elegans) antibody, ubiquitin conjugating enzyme E2G 1 (uBC7 homolog yeast), ubiquitin conjugating enzyme E2G 1, ubiquitin protein ligase G1, |
