| MW: | 27kDa |
| Purity: | >95% as determined by SDS-PAGE |
| Description: | Human CD226/DNAM-1 protein, His tag (Animal-Free), expressed in HEK 293 Cells |
| Further Information: | The adhesion receptor CD226 (DNAM-1) is a member of the Ig superfamily possessing two extracellular V-like domains. In humans, CD226 was shown to be expressed by NK as well as T cells. During T cell priming, CD226-mediated costimulatory signals may skew the subsequent differentiation into the Th1 pathway. In addition, CD226 expressed on NK and cytotoxic T cells is engaged by its counter-receptor CD155, present on target cells, thereby triggering their elimination.CD226 represents receptor-activating cytotoxic T lymphocyte and natural killer cells taking part in tumor surveillance, the pathogenesis of inflammation, and autoimmune disorders. |
| NCBI EntrezGene: | 10666 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Lyophilized Human CD226/DNAM-1 protein, His tag (Animal-Free)should be stored desiccated below -20 C. Upon reconstitution, the protein should be stored at 4 C between 2-7 days and for future use below -20 C. For long term storage it is recommended to add a carrier protein (0.117% HSA or BSA). Please prevent freeze-thaw cycles. |
| Usage: | Research use only |
