| MW: | 27.3 kDa |
| Purity: | >95% as determined by SDS-PAGE |
| Description: | Human CD33/Siglec-3 protein, His tag (Animal-Free), expressed in HEK 293 Cells |
| Further Information: | The transmembrane protein CD33 is a sialic acid-binding immunoglobulin-like lectin that mediate the cell-cell interaction and inhibiting normal functions of immune cells. CD33 (siglec-3), a well-known target in leukemia therapy, is an inhibitory sialoadhesin expressed in human leukocytes of the myeloid lineage and some lymphoid subsets, including NK cells. It may constitute a control mechanism of the innate immune system. In the brain, CD33 is mainly expressed on microglial cells. |
| NCBI EntrezGene: | 945 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Lyophilized Human CD33/Siglec-3 protein, His tag (Animal-Free)should be stored desiccated below -20 C. Upon reconstitution, the protein should be stored at 4 C between 2-7 days and for future use below -20 C. For long term storage it is recommended to add a carrier protein (0.111% HSA or BSA). Please prevent freeze-thaw cycles. |
| Usage: | Research use only |
