Human CD38 protein, His tag (Animal-Free)

MW:	31 KD
Purity:	>95% as determined by SDS-PAGE.
Description:	Human CD38 protein, His tag (Animal-Free), expressed in HEK293 Cells
Further Information:	CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+�into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+, and ADP-ribose .CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. CD38 is expressed in B�and T�lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells . Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic ? �cells.
NCBI EntrezGene:	952
Shipping Conditions:	Ship on cold packs
Storage:	Lyophilized Human CD38 protein, His tag (Animal-Free)should be stored desiccated below -20 C. Upon reconstitution, the protein should be stored at 4 C between 2-7 days and for future use below -20 C. For long term storage it is recommended to add a carrier protein (0.103% HSA or BSA). Please prevent freeze-thaw cycles.
Usage:	Research use only