| MW: | 18 kDa |
| Purity: | >98 % as determined by SDS-PAGE |
| Description: | Human IL-33 protein, expressed in E. coli |
| Further Information: | Interleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial enules), is a proinflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 protein is expressed highly and rather selectively by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyers's patches, and lymph nodes. IL-33 protein has transcriptional regulatory properties, and the researchers suggested that IL-33 is a dual-function protein that might act both as a cytokine and as an intracellular nuclear factor. As a type 2 cytokines, IL-33 protein also plays a pivotal role in helminthic infection and allergic disorders. |
| NCBI EntrezGene: | 90865 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Lyophilized Human IL-33 proteinshould be stored desiccated below -20 C. Upon reconstitution, the protein should be stored at 4 C between 2-7 days and for future use below -20 C. For long term storage it is recommended to add a carrier protein (0.8% HSA or BSA). Please prevent freeze-thaw cycles. |
| Usage: | Research use only |
