| Description: | Protein arginine N-methyltransferase 1 (PRMT1) is a type I methyltransferase that transfers a methyl group from S-adenosylmethionine to guanidino nitrogens of arginine residues to form monomethylarginine and asymmetric dimethylarginine. Functions of type I arginine methylation in proteins may include regulation of transcription, modulation of the affinity of nucleic acid-binding proteins, regulation of interferon signaling pathways, and targeting of nuclear proteins. Mouse PRMT1 (AAF37293) shares 99. 9% sequence identity with the human proteins (NP_938074). Recombinant mouse PRMT1, fused to His-MBP tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
| Synonym: | Protein arginine N-methyltransferase 1, Mrmt1, Hrmt112, AW214366, Protein arginine N-methytransferase 1, PRMT1 isoform2, PRMT1, Protein arginine N-methyltransferase 1 ANM 1, HCP 1, HMT1 hnRNP methyltransferase, Heterogeneous nuclear ribonucleoproteins methyltransferase like 2, HMT2, HRMT1 L2, HRMT1L 2, Heterogeneous nuclear ribonucleoproteins methyltransferase like2, HMT 2, HMT1 (hnRNP methyltransferase S, cerevisiae) like 2, HMT1 hnRNP methyltransferase like 2, HMT1 hnRNP methyltransferase like 2 (S, cerevisiae), Human mRNA for suppressor for yeast mutant, Human mRNA for suppressor for yeast mutant complete cds, Interferon receptor 1 bound protein 4, Interferon receptor 1 bound protein4, Interferon receptor 1bound protein 4, IR1 B4, IR1B 4, Mrmt 1, Mrmt1, PRMT 1, R1B4, S, cerevisiae like 2, Protein arginine N methyltransferase 1, Protein arginine N methyltransferase1, |
