GFAP, Monoclonal Antibody
Partner: Aviva Systems Biology
| Applications: | WB, IHC, ICC, IF |
| Species Reactivity: | Human, Mouse, Rat |
| Dilutions: | WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Immunogen: | Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse |
| Purification: | Protein G Purified |
| Conjugation: | Unconjugated |
| Description: | The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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