Data Sheet

TrpC5, Monoclonal Antibody

Applications:	WB, IHC, IP, AM
Species Reactivity:	Human, Mouse, Rat
Dilutions:	WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Immunogen:	Synthetic peptide amino acids 827-845 of human TrpC5 (also known as short transient receptor potential channel 5, and Htrp5)
Purification:	Protein G Purified
Conjugation:	Unconjugated
Description:	Transient receptor potential cation channel, subfamily C, member 5, also known as TRPC5, is a subtype of the TRPC family of mammalian transient receptor potential ion channels. Homo-multimeric TRPC5 and hetero-multimeric TRPC5-TRPC1 channels are activated by extracellular reduced thioredoxin (1). This activation probably plays a role in rheumatoid arthritis. It has also been recently found to be involved in the action on anaesthetics such as chloroform, halothane and propofol (2).
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only