Data Sheet

TrpC7, Monoclonal Antibody

Applications:	WB, IHC, ICC, IF, IP, AM
Species Reactivity:	Human, Mouse, Rat
Dilutions:	WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Immunogen:	Synthetic peptide amino acids 845-862 of human TRPC7
Purification:	Protein G Purified
Conjugation:	Unconjugated
Description:	Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a non-selective cation channel that is directly activated by DAG. TrpC7 shows constitutive activity and susceptibility to negative regulation by extracellular Ca2+. Because of this, TrpC7 plays an important role in the Ca2+ signaling pathway (1). TrpC7 is also expressed abundantly in the heart, and combined with its ability to act as a Ca2+ channel, TrpC7 might contribute to the process of heart failure (2).
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only