BK beta2, Monoclonal Antibody
Partner: Aviva Systems Biology
| Applications: | WB, IHC, ICC, IF, IP, AM |
| Species Reactivity: | Human, Mouse, Rat |
| Dilutions: | WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user. |
| Immunogen: | Fusion protein amino acids 1-41 (N-terminus) and 218-235 (C-terminus) of mouse BKBeta2 |
| Purification: | Protein G Purified |
| Conjugation: | Unconjugated |
| Description: | BK channels contribute to electrical impulses, proper signal transmission of information and regulation of neurotransmitter release (1). A gain of function mutation in the pore-forming alpha subunit of the BK channel was linked to human neurological diseases. Findings suggest that the distribution of the beta subunits in the brain can modulate the BK channels to contribute to the pathophysiology of epilepsy and dyskinesia (2). This has major implications on other physiological processes in tissues other than the brain. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
Insight Biotechnology Ltd reserves the right to change pricing without notice
