Applications: | WB, IHC, ICC, IF, IP, AM |
Species Reactivity: | Human, Mouse, Rat, Hamster |
Dilutions: | WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user. |
Immunogen: | Fusion protein amino acids 2-101 of human KCNQ1 |
Purification: | Protein G Purified |
Conjugation: | Unconjugated |
Description: | Kv7.1 (KvLQT1) is a potassium channel protein coded for by the gene KCNQ1. Kv7.1 is present in the cell membranes of cardiac muscle tissue and in inner ear neurons (1) among other tissues. In the cardiac cells, Kv7.1 mediates the IKs (or slow delayed rectifying K+) current that contributes to the repolarization of the cell, terminating the cardiac action potential and thereby the heart's contraction (2, 3). |
Shipping Conditions: | Ship on cold packs |
Usage: | Research Use Only |