| Applications: | Flow Cytometry, IP, WB, IHC-F, ICC |
| Species Reactivity: | Mouse, Human |
| Isotype: | Mouse IgG1 |
| Immunogen: | Purified human CD3 proteins isolated from thymus. The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation. |
| Purification: | Purified by protein-A affinity chromatography. |
| MW: | 23147 MW |
| Description: | Boster Bio Anti-CD3 epsilon (activation epitope) Purified Monoclonal Antibody (Catalog # M02675-4). Tested in Flow Cytometry, IP, WB, IHC-F, ICC application(s). This antibody reacts with Mouse, Human. |
| Synonym: | CD3 epsilon chain, T3E, IMD18 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Store at 2-8 C. Do not freeze. |
| Usage: | Research use only |
