| Applications: | IP,IF,IHC,ICC,WB |
| Species Reactivity: | Human,Rat |
| Isotype: | Rabbit IgG |
| Immunogen: | A synthesized peptide derived from human APC Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF) -induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. |
| Purification: | Affinity-chromatography |
| Description: | Boster Bio Anti-APC Monoclonal Antibody catalog # M00008. Tested in IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Store at -20�C for one year. For short term storage and frequent use, store at 4�C for up to one month. Avoid repeated freeze-thaw cycles. |
| Usage: | Research Use Only |
