Further Information: | TPX belongs to the family of peroxidases. It mainly achieves anti-oxidation by reducing hydrogen peroxide and some hydroperoxides in the body. It functions similarly to GPX and is one of the key enzymes in the glutathione redox cycle. TPX is ubiquitous in various organisms, such as yeast, plants, animals, protozoa, parasites, bacteria, and archaea, and is highly conservative in evolution. TPX is closely related to the regulation of cell proliferation, differentiation, apoptosis and tumorigenesis. The main functions of TPX include cell detoxification, anti-oxidation, and regulation of signal transduction and immune response mediated by hydrogen peroxide. |