4?-DTMP [CAS 21253-58-7]
Partner: MedChemexpress LLC
| CAS No: | 21253-58-7 |
| MW: | 276.29 |
| Formula: | C13H16N4O3 |
| SMILES: | OC1=C(OC)C=C(CC2=CN=C(N)N=C2N)C=C1OC |
| Purity: | 97.0 |
| Description: | 4 '-DTMP is a DHFR inhibitor with Ki of 5.1 nM (DHFRWT) and 34.3 nM (DHFRL28R), respectively. 4 '-DTMP carries a polar modification that induces additional local interactions with the enzyme. In particular, the hairpin structure on the M20 ring is related to the internal communication of the DHFR. 4 '-DTMP has potential inhibition of E.coli[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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