RO8191 [CAS 691868-88-9]
Partner: MedChemexpress LLC
| CAS No: | 691868-88-9 |
| Applications: | COVID-19-anti-virus |
| MW: | 373.21 |
| Formula: | C14H5F6N5O |
| SMILES: | FC(C1=C2C=CC3=NC(C4=NN=CO4)=CN3C2=NC(C(F)(F)F)=C1)(F)F |
| Purity: | 99.0 |
| Description: | RO8191 (CDM-3008), an imidazonaphthyridine compound, is an orally active and potent interferon (IFN) receptor agonist. RO8191 directly binds to IFN?/? receptor 2 (IFNAR2) and activates IFN-stimulated genes (ISGs) expression and JAK/STAT phosphorylation. RO8191 shows antiviral activity against both HCV and EMCV with an IC50 of 200 nM for HCV replicon[1]. RO8191 is a cccDNA modulator (CDM) through interferon-like activity and has anti-HBV activity[2]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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