Data Sheet

MSDS

Zimberelimab [CAS 2259860-24-5]

CAS No:	2259860-24-5
Applications:	Cancer-programmed cell death
MW:	N/A
Formula:	N/A
SMILES:	[Zimberelimab]
Purity:	99.90
Description:	Zimberelimab (GLS-010) is a fully human IgG4 anti-PD-1 monoclonal antibody with an EC50 of 210 pM for human PD-1. Zimberelimab effectively blocks the binding of PD-L1 and PD-L2 to cell-surface PD-1 in CHO-S cells, with IC50 values of 580 pM and 670 pM, respectively. Zimberelimab shows antitumor activities, and can be used for various cancers research, including cervical cancer, non-small cell lung cancer and classical Hodgkin�s lymphoma[1][2].
Shipping Conditions:	Ship on dry ice
Usage:	Research Use Only