| Description: | Peroxiredoxin-1 (PRDX1), a thiol-specific peroxidase, catalyzes the reduction of hydrogen peroxide and organic hydroperoxides, playing a crucial role in cellular protection against oxidative stress. It detoxifies peroxides and senses hydrogen peroxide-mediated signaling events. PRDX1 may contribute to signaling cascades initiated by growth factors and tumor necrosis factor-alpha, potentially influencing intracellular H(2)O(2) concentrations. Notably, PRDX1 reduces an intramolecular disulfide bond in GDPD5, modulating its capacity to drive postmitotic motor neuron differentiation. These multifaceted functions underscore PRDX1's intricate involvement in redox signaling and cellular differentiation processes. Peroxiredoxin-1 protein, Human (P. pastoris, His) is the recombinant human-derived Peroxiredoxin-1 protein, expressed by P. pastoris, with C-6*His labeled tag. The total length of Peroxiredoxin-1 protein, Human (P. pastoris, His) is 199 a.a., with molecular weight of ~22.1 kDa. |
