| Description: | Apolipoprotein E/APOE is pivotal in lipid transport, participating in the production, conversion, and clearance of plasma lipoproteins. It interacts with various particles, including chylomicrons and HDL, and binds to cellular receptors like LDLR and VLDLR, facilitating uptake. APOE's heparin-binding activity supports lipoprotein capture, while forming a homotetramer and collaborating with ABCA1 in HDL biogenesis. It may also interact with various proteins, including APP, MAPT, MAP2, and SORL1, as well as PMEL in cerebrospinal fluid, inducing fibril nucleation. Apolipoprotein E/APOE Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Apolipoprotein E/APOE protein, expressed by HEK293, with C-hFc labeled tag. The total length of Apolipoprotein E/APOE Protein, Mouse (HEK293, Fc) is 293 a.a., with molecular weight of 62-66 kDa. |
