| Description: | HIST2H2BE protein serves as a core component of the nucleosome, a pivotal structure in chromatin organization that wraps and compacts DNA, controlling its accessibility to cellular machineries dependent on DNA templates. This integral role of histones, including HIST2H2BE, extends to transcriptional regulation, DNA repair, DNA replication, and chromosomal stability. The accessibility of DNA is finely tuned through a sophisticated array of post-translational modifications known as the histone code, alongside nucleosome remodeling processes. Beyond its involvement in chromatin dynamics, HIST2H2BE exhibits broad antibacterial activity, suggesting its potential contribution to the establishment of a functional antimicrobial barrier in the colonic epithelium and the bactericidal activity observed in amniotic fluid. HIST2H2BE Protein, Human is the recombinant human-derived HIST2H2BE protein, expressed by E. coli , with tag free. The total length of HIST2H2BE Protein, Human is 126 a.a., with molecular weight of ~16 KDa. |
