| Description: | 14-3-3 epsilon protein, an adapter in diverse signaling pathways, binds phosphoserine or phosphothreonine motifs, modulating partner activity. It positively regulates HSF1 nuclear export to the cytoplasm, forming homodimers and heterodimers with YWHAZ. Interactions include PKA-phosphorylated AANAT, phosphorylated ABL1, ARHGEF28, BEX3, CDKN1B, phosphorylated DAPK2, DENND1A, GAB2, phosphorylated GRB10, KSR1, NDEL1, PI4KB, TBC1D22A, TBC1D22B, phosphorylated SRPK2, TIAM2, phosphorylated SOS1, ZFP36, SLITRK1, phosphorylated HSF1, RIPOR2, KLHL22, CRTC1, phosphorylated CRTC2, phosphorylated CRTC3, ATP2B1, ATP2B3, and MEFV, illustrating its multifunctional role. 14-3-3 epsilon Protein, Mouse (His) is the recombinant mouse-derived 14-3-3 epsilon protein, expressed by E. coli, with N-6*His labeled tag. The total length of 14-3-3 epsilon Protein, Mouse (His) is 255 a.a., with molecular weight of ~48 kDa. |
