| Description: | MTH1 Protein, functioning as an oxidized purine nucleoside triphosphate hydrolase, crucially safeguards the cellular nucleotide pool. It catalyzes the hydrolysis of oxidized purine nucleoside triphosphates, such as 2-oxo-dATP and 8-oxo-dGTP, preventing their incorporation into DNA and averting transversions in base pairs. MTH1's antimutagenic activity extends to blocking the integration of methylated purine nucleoside triphosphates into DNA, highlighting its vital role in preserving genomic stability and mitigating oxidative stress impact on cellular processes. MTH1 Protein, Human (His) is the recombinant human-derived MTH1 protein, expressed by E. coli, with N-His labeled tag. The total length of MTH1 Protein, Human (His) is 156 a.a., with molecular weight of ~20.2 kDa. |
