| Description: | CD84/SLAMF5, a self-ligand receptor of the SLAM family, modulates immune cell activation and differentiation through homo- or heterotypic interactions. Its activities are influenced by SH2D1A/SAP and SH2D1B/EAT-2. CD84/SLAMF5 plays roles in NK cell cytotoxicity, T-cell proliferation, interferon gamma secretion, platelet stimulation, hematopoietic progenitor cell marking, and germinal center functions. It contributes to B cell tolerance, prevents autoimmunity, regulates mast cell signaling, and enhances macrophage responses. The protein forms homodimers and interacts with various signaling molecules. CD84/SLAMF5 Protein, Mouse (221a.a, HEK293, His) is the recombinant mouse-derived CD84/SLAMF5 protein, expressed by HEK293, with C-10*His labeled tag. The total length of CD84/SLAMF5 Protein, Mouse (221a.a, HEK293, His) is 200 a.a., with molecular weight of 37-42 kDa. |
