| Description: | The T-PA protein, encoded by this gene, is a secreted serine protease that converts plasminogen to plasmin, a crucial enzyme involved in tissue remodeling and cell migration. Proteolytic processing generates heavy and light chains, forming the heterodimeric enzyme. T-PA's enzymatic activity is vital for maintaining the balance between fibrinolysis and coagulation. Increased activity causes excessive bleeding, while decreased activity can lead to thrombosis. Alternative splicing produces multiple isoforms. The gene shows broad expression across various tissues, reflecting its diverse physiological roles. T-PA Protein, Human (HEK293) is the recombinant human-derived T-PA protein, expressed by HEK293, with tag free. The total length of T-PA Protein, Human (HEK293) is 252 a.a., with molecular weight of ~35 kDa. |
