| Description: | The Nucleolar transcription factor 1/UBTF protein crucially activates RNA polymerase I-mediated transcription by binding to the ribosomal RNA gene promoter and cooperating with the SL1/TIF-IB complex. As a homodimer, UBTF interacts with proteins like TBP, TAF1A, RASL11A, IRS1, and PIK3CA, revealing its regulatory role in ribosomal RNA gene transcription and involvement in diverse cellular processes related to transcriptional control and nucleolar function. Nucleolar transcription factor 1/UBTF Protein, Human (His-SUMO) is the recombinant human-derived Nucleolar transcription factor 1/UBTF protein, expressed by E. coli, with N-SUMO, N-6*His labeled tag. The total length of Nucleolar transcription factor 1/UBTF Protein, Human (His-SUMO) is 670 a.a., with molecular weight of ~95.0 kDa. |
