| Description: | M�llerian-inhibiting factor (AMH) plays a crucial role in various reproductive processes. In male fetal sexual differentiation, it contributes significantly to M�llerian duct regression. In adults, AMH is involved in Leydig cell differentiation, while in females, it negatively regulates follicle transition and reduces FSH sensitivity. AMH acts through its sole type II receptor, AMHR2, recruiting type I receptors ACVR1 and BMPR1A, activating the Smad pathway. As a homodimer with disulfide linkages, AMH orchestrates key events in male and female reproductive development. Muellerian-inhibiting factor/AMH Protein, Mouse is the recombinant mouse-derived Muellerian-inhibiting factor/AMH protein, expressed by E. coli, with tag free. The total length of Muellerian-inhibiting factor/AMH Protein, Mouse is 103 a.a., with molecular weight of ~14 kDa. |
