Description: | Angiogenin-4 protein exhibits bactericidal activity specifically against E. faecalis and L. monocytogenes, distinguishing its antimicrobial effects from its lack of efficacy against L. innocua and E. coli. Moreover, Angiogenin-4 plays a role in promoting angiogenesis in vitro, suggesting its involvement in supporting the formation of new blood vessels. Although it possesses low ribonuclease activity in vitro, its impact on promoting the proliferation of melanoma cells is notable, while showing no similar effect on endothelial cells or fibroblasts in vitro. These diverse activities underscore the multifunctional nature of Angiogenin-4, suggesting its potential significance in both antimicrobial defense and cellular processes related to angiogenesis and cell proliferation. Angiogenin-4 Protein, Mouse (P.pastoris) is the recombinant mouse-derived Angiogenin-4 protein, expressed by P. pastoris , with N-6*His, N-SUMO labeled tag. The total length of Angiogenin-4 Protein, Mouse (P.pastoris) is 120 a.a., with molecular weight of ~33 kDa. |