| Description: | TIMP-1, a metalloproteinase inhibitor, irreversibly inactivates collagenases and other metalloproteinases by binding to their catalytic zinc cofactor. It regulates MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13, and MMP16, and influences cellular processes like differentiation, migration, and cell death. TIMP-1 activates signaling cascades through interactions with CD63 and ITGB1 and engages in protein-protein interactions with MMP1, MMP3, MMP10, and MMP13, indicating its regulatory role. It also participates in intricate cellular signaling networks with CD63 and ITGB1. TIMP-1 Protein, Mouse (HEK293) is the recombinant mouse-derived TIMP-1 protein, expressed by HEK293, with tag free. The total length of TIMP-1 Protein, Mouse (HEK293) is 181 a.a., with molecular weight of ~26.0 kDa. |
