| Description: | TFRC protein facilitates cellular iron uptake through receptor-mediated endocytosis. TFRC is crucial for erythrocyte and nervous system development and plays a vital role in iron homeostasis. It competes with HFE for binding and positively regulates T and B cell proliferation. TFRC also acts as a lipid sensor, modulating mitochondrial fusion through the JNK pathway. Additionally, TFRC acts as a receptor for new-world arenaviruses during microbial infection. TFRC Protein, Human (HEK293, His) is the recombinant human-derived TFRC protein, expressed by HEK293, with N-6*His labeled tag. The total length of TFRC Protein, Human (HEK293, His) is 660 a.a., with molecular weight of 78-90 kDa. |
