Description: | MORF4L2 protein, an essential component of the NuA4 histone acetyltransferase complex, facilitates transcriptional activation by acetylating histones H4 and H2A. This modification alters nucleosome-DNA interactions and promotes interactions with other transcriptionally positive proteins. MORF4L2's role in the NuA4 complex is pivotal for cellular processes like growth, senescence, apoptosis, and DNA repair. Additionally, it is part of the MSIN3A complex, contributing to transcriptional repression through histone deacetylation. MORF4L2's interactions with various subunits emphasize its intricate involvement in chromatin modification and gene regulation. MORF4L2 Protein, Human (His) is the recombinant human-derived MORF4L2 protein, expressed by E. coli, with C-6*His labeled tag. The total length of MORF4L2 Protein, Human (His) is 288 a.a., with molecular weight of 33-36 kDa. |