| Description: | IgG4 Fc, the constant region of immunoglobulin heavy chains, forms the backbone of antibodies crucial in humoral immunity. B lymphocytes produce glycoprotein antibodies, initiating clonal expansion upon antigen binding. Membrane-bound immunoglobulins act as receptors, driving B lymphocyte differentiation into plasma cells. The secreted immunoglobulins eliminate bound antigens, each possessing two antigen-binding sites formed by variable domains. Immunoglobulins undergo V-(D)-J rearrangement and somatic hypermutations for affinity maturation. The intricate molecular architecture highlights their pivotal role in immune recognition and response. IgG4 Fc Protein, Human (HEK293) is the recombinant human-derived IgG4 Fc protein, expressed by HEK293, with tag free. The total length of IgG4 Fc Protein, Human (HEK293) is 228 a.a., with molecular weight of ~32.0 kDa. |
