| Description: | Leptin, a key regulator of energy balance and body weight, binds to LEPR receptors in various tissues. It controls appetite in the hypothalamus and affects bone mass, hormone regulation, and reproductive function. In peripheral tissues, it boosts metabolism, impacts pancreatic function, and promotes angiogenesis. Leptin activates POMC neurons and inhibits NPY neurons in the arcuate nucleus, regulating anorexigenic and orexigenic peptides. It also modulates nutrient absorption, gene expression, immune responses, and T-cell proliferation through various signaling pathways. Leptin Protein, Mouse (His) is the recombinant mouse-derived Leptin protein, expressed by E. coli, with N-6*His labeled tag. The total length of Leptin Protein, Mouse (His) is 146 a.a., with molecular weight of ~17 kDa. |
