| Description: | IL-1 beta Protein, a potent pro-inflammatory cytokine, plays diverse roles in immune responses. It induces inflammatory events, including prostaglandin synthesis, neutrophil activation, and cytokine production. IL-1 beta promotes Th17 differentiation, synergizes with IL-12 for IFNG synthesis, and contributes to angiogenesis through VEGF induction. Released through pyroptosis, it acts as a sensor of S. pyogenes infection, inducing an inflammatory response. However, IL-1 beta cleavage by SpeB has a dual role, promoting streptococcal infection in the nasopharynx. IL-1 beta Protein, Human (solution) is the recombinant human-derived IL-1 beta protein, expressed by E. coli, with tag free. The total length of IL-1 beta Protein, Human (solution) is 153 a.a., with molecular weight of ~16.61 kDa. |
