| Description: | SCF Protein, a ligand for KIT receptor-type protein-tyrosine kinase, crucially regulates diverse cellular processes, including survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Binding to KIT activates multiple signaling pathways involving PIK3R1, AKT1, GRB2, RAS, RAF1, MAP kinases, STAT family members, and PLCG1, producing signaling molecules. Acting with likely interleukins, SCF forms homodimers and a heterotetramer with KIT, facilitating dimerization and autophosphorylation for activation. SCF Protein, Mouse (HEK293, His) is the recombinant mouse-derived SCF protein, expressed by HEK293, with C-6*His labeled tag. The total length of SCF Protein, Mouse (HEK293, His) is 164 a.a., with molecular weight of 19-35 kDa. |
