| Description: | Apolipoprotein E/APOE, vital for lipid transport, is integral in plasma lipoprotein production, conversion, and clearance. It interacts with various particles, favoring HDL, and binds to receptors like LDLR and VLDLR, facilitating cellular uptake. APOE's heparin-binding activity aids lipoprotein capture and uptake. It forms a homotetramer, collaborates with ABCA1 in HDL biogenesis, and interacts with proteins like APP, MAPT, MAP2, SORL1, and PMEL in diverse physiological processes, including fibril nucleation. Apolipoprotein E/APOE Protein, Rat (His) is the recombinant rat-derived Apolipoprotein E/APOE protein, expressed by E. coli, with N-6*His labeled tag. The total length of Apolipoprotein E/APOE Protein, Rat (His) is 294 a.a., with molecular weight of 39.8 kDa. |
