Description: | Activin B, a TGF? superfamily cytokine, is a homodimer of activin ?B subunits. Activin B binds to type II transmembrane serine-threonine kinase receptors (ACTRIIA or ACTRIIB) which, in turn, activate type I receptors (ACTRI) that phosphorylate and activate canonical SMAD signaling pathways[1][2]. Animal-Free Activin B Protein, Human (His), a recombinant animal-free protein, is produced in E. coli with a C-Terminal His-tag. It consists of 115 amino acids (G293-407A). |