Description: | ?C-Conotoxin PrXA is a paralytic peptide neurotoxin and a competitive nAChR antagonist, with IC50s of 1.8 nM (?1?1??, adult) and 3.0 nM (?1?1??, fetal), respectively. ?C-Conotoxin PrXA competes with ?-bungarotoxin at the ?/? and ?/? subunit interfaces of the nAChR, shows high specificity against neuromuscular nAChR[1]. |