YAP-TEAD-IN-1 (TFA) [CAS 1659305-79-9]
Partner: MedChemexpress LLC
| CAS No: | 1659305-79-9 |
| Applications: | Cancer-programmed cell death |
| MW: | 2133.88 |
| Formula: | C95H145F3ClN23O23S2 |
| SMILES: | O=C(N(CCC1)[C@@H]1C(N[C@H](C(N)=O)CCC(O)=O)=O)[C@H](CCC2)N2C([C@H](CCCCN)NC(C(CSSCC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H]3CCCCN)=O)CCCNC(N)=N)=O)CC(C)C)=O)NC([C@H](CC4=CC(Cl)=CC=C4)NC([C@H](CCC5)N5C([C@H](C(C)C)NC(C)=O)=O)=O)=O)NC([C@@H](NC([C@](NC([C@@H](NC([C@@](CCC6)([H])N6C([C@](NC3=O)([H])CCCC)=O)=O)C)=O)([H])CO)=O)CC7=CC=CC=C7)=O)=O)=O.OC(C(F)(F)F)=O.[x] |
| Purity: | 99.60 |
| Description: | YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of�YAP-TEAD interaction (IC50=25 nM). YAP-TEAD-IN-1 TFA is a 17mer peptide and shows a higher the binding affinity to TEAD1 (Kd=15 nM) than YAP (50-171) (Kd= 40 nM)[1]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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