Deoxyshikonin [CAS 43043-74-9]
Partner: MedChemexpress LLC
CAS No: | 43043-74-9 |
Applications: | Cancer-programmed cell death |
MW: | 272.30 |
Formula: | C16H16O4 |
SMILES: | O=C1C(CC/C=C(C)/C)=CC(C2=C1C(O)=CC=C2O)=O |
Purity: | 99.96 |
Description: | Deoxyshikonin increases the expression of VEGF-C and VEGF-A mRNA in HMVEC-dLy, promotes HIF-1α and HIF-1β subunit interaction and binds to specific DNA sequences targeted by HIF. Deoxyshikonin inhibited colorectal cancer (CRC) through the PI3K/Akt/mTOR pathway. Deoxyshikonin has proangiogenesis effect and antitumor activity. Deoxyshikonin is an antibacterial agent against methicillin-resistant S. aureus (MRSA) and S. pneumonia (MIC=17 μg/mL)[1][2][3]. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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