Data Sheet

MSDS

5-O-Demethylnobiletin [CAS 2174-59-6]

CAS No:	2174-59-6
Applications:	COVID-19-immunoregulation
MW:	388.37
Formula:	C₂₀H₂₀O₈
SMILES:	O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=C(OC)C(OC)=C(OC)C(O)=C13
Purity:	99.93
Description:	5-O-Demethylnobiletin (5-Demethylnobiletin), a polymethoxyflavone isolated from Citrus jambhiri Lush., is a direct inhibition of 5-LOX (IC50=0.1 ?M), without affecting the expression of COX-2. 5-O-Demethylnobiletin (5-Demethylnobiletin) has anti-inflammatory activity, inhibits leukotriene B (4)(LTB4) formation in rat neutrophils and elastase release in human neutrophils with an IC50 of 0.35 ?M[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only