Data Sheet

MSDS

BMX-IN-1 [CAS 1431525-23-3]

CAS No:	1431525-23-3
Applications:	Cancer-Kinase/protease
MW:	524.59
Formula:	C₂₉H₂₄N₄O₄S
SMILES:	O=C1N(C2=C(C=C1)C=NC3=CC=C(C4=CC=C(NS(=O)(C)=O)C=C4)C=C32)C5=CC=C(C)C(NC(C=C)=O)=C5
Purity:	99.84
Description:	BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Bruton�s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only