Alosetron (Hydrochloride) [CAS 122852-69-1]
Partner: MedChemexpress LLC
| CAS No: | 122852-69-1 |
| Applications: | Neuroscience-Neuromodulation |
| MW: | 330.81 |
| Formula: | C17H19ClN4O |
| SMILES: | O=C(C(C1=C2C=CC=C1)=C(N2C)CC3)N3CC4=C(NC=N4)C.[H]Cl |
| Purity: | 99.76 |
| Description: | Alosetron Hydrochloride (GR 68755C) is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron Hydrochloride is used for the research of irritable bowel syndrome (IBS). Alosetron blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC50 at ~55 nM. Alosetron Hydrochloride attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects[1][2]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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