BRD3308 [CAS 1550053-02-5]
Partner: MedChemexpress LLC
| CAS No: | 1550053-02-5 |
| Applications: | COVID-19-anti-virus |
| MW: | 287.29 |
| Formula: | C15H14FN3O2 |
| SMILES: | O=C(C)NC1=CC=C(C(NC2=CC=C(F)C=C2N)=O)C=C1 |
| Purity: | 98.07 |
| Description: | BRD3308 is a highly selective HDAC3 inhibitor with an IC50 of 54 nM. BRD3308 is 23-fold selectivity for HDAC3 over HDAC1 (IC50 of 1.26 ?M) or HDAC2 (IC50 of 1.34 ?M). BRD3308 suppresses pancreatic ?-cell apoptosis induced by inflammatory cytokines or glucolipotoxic stress, and increases functional insulin release. BRD3308 activates HIV-1 transcription and disrupts HIV-1 latency[1][2][3]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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