OSU-T315 [CAS 2070015-22-2] (10mM in DMSO)
Partner: MedChemexpress LLC
| CAS No: | 2070015-22-2 |
| Applications: | Cancer-Kinase/protease |
| MW: | 533.59 |
| Formula: | C30H30F3N5O |
| SMILES: | O=C(NC)CCC1=CC(C2=CC=C(C3=CC=C(C(F)(F)F)C=C3)C=C2)=NN1C4=CC=C(N5CCNCC5)C=C4 |
| Purity: | 99.88 |
| Description: | OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0.6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain)[1]. OSU-T315 abrogates AKT activation by impeding AKT localization in lipid rafts and triggers caspase-dependent apoptosis in an ILK-independent manner[2]. OSU-T315 causes cell death through apoptosis and autophagy[1]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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