RU-SKI 43 (hydrochloride) [CAS 1782573-67-4] (10mM in DMSO)
Partner: MedChemexpress LLC
| CAS No: | 1782573-67-4 |
| Applications: | Cancer-Kinase/protease |
| MW: | 423.01 |
| Formula: | C22H31ClN2O2S |
| SMILES: | [H]Cl.O=C(CNCC(C)CC)N1CCC2=C(C=CS2)C1COC3=CC=CC(C)=C3 |
| Purity: | 99.55 |
| Description: | RU-SKI 43 hydrochloride is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. RU-SKI 43 hydrochloride reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. RU-SKI 43 hydrochloride has anti-cancer activity[1]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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