S1RA [CAS 878141-96-9] (10mM in DMSO)
Partner: MedChemexpress LLC
| CAS No: | 878141-96-9 |
| Applications: | Neuroscience-Neuromodulation |
| MW: | 337.42 |
| Formula: | C20H23N3O2 |
| SMILES: | CC1=CC(OCCN2CCOCC2)=NN1C3=CC(C=CC=C4)=C4C=C3 |
| Purity: | 99.43 |
| Description: | S1RA (E-52862) is a highly selective ?1 receptor (?1R) antagonist with Kis of 17 nM and 23.5 nM for human ?1R and guinea pig ?1R, respectively. S1RA has Moderate antagonistic activity for human 5-HT2B receptor (Ki= 328 nM). S1RA has antinociceptive effects in neuropathic pain models. S1RA prevents mechanical and cold hypersensitivity in Oxaliplatin (HY-17371)-treated mice[1][2]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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