Data Sheet

MSDS

Embelin [CAS 550-24-3] (10mM in DMSO)

CAS No:	550-24-3
Applications:	Cancer-programmed cell death
MW:	294.39
Formula:	C₁₇H₂₆O₄
SMILES:	O=C1C(O)=C(CCCCCCCCCCC)C(C(O)=C1)=O
Purity:	98.75
Description:	Embelin (Embelic acid), a potent, nonpeptidic XIAP inhibitor (IC50=4.1 ?M), inhibits cell growth, induces apoptosis, and activates caspase-9 in prostate cancer cells with high levels of XIAP. Embelin blocks NF-kappaB signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. Embelin also induces autophagic and apoptotic cell death in human oral squamous cell carcinoma cells[1][2][3].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only