AFN-1252 [CAS 620175-39-5]
Partner: MedChemexpress LLC
| CAS No: | 620175-39-5 |
| Applications: | COVID-19-immunoregulation |
| MW: | 375.42 |
| Formula: | C22H21N3O3 |
| SMILES: | O=C(N(C)CC1=C(C)C2=CC=CC=C2O1)/C=C/C(C=C3CC4)=CNC3=NC4=O |
| Purity: | 98.51 |
| Description: | AFN-1252 is an orally active and selective inhibitor of FabI, an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 exhibits exquisite and highly selective activity against Staphylococcus spp. AFN-1252 exhibits typical MIC90 values of ?0.015 ?g/ml against diverse clinical isolates of S. aureus. AFN-1252 is efficacious in a mouse model of septicemia providing 100% protection from an otherwise lethal peritoneal infection of S. aureus Smith[1][2]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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