Data Sheet

MSDS

Camptothecin [CAS 7689-03-4] (10mM in DMSO)

CAS No:	7689-03-4
Applications:	Cancer-programmed cell death
MW:	348.35
Formula:	C₂₀H₁₆N₂O₄
SMILES:	O=C1C2=C([C@@](O)(CC)C(OC2)=O)C=C(N1C3)C(C3=C4)=NC5=C4C=CC=C5
Purity:	99.82
Description:	Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1]. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1? (HIF-1?) activity by changing microRNAs (miRNA) expression patterns in human cancer cells[2][3].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only